I hope Wolfram Alpha does well ... I really do. I've thought for awhile that Google really needs a viable competitor, which will help drive search forward. However, I'll wait until the site is launched before announcing them as a serious competitor (even then, I'm willing to give them months or years if their product holds promise, AND they demonstrate the ability to roll out improvements on a regular basis). I'd also be interested to see if they have an API, and how easy it would be to tap into their system to create vertical apps.
So here's the link for today from the popular (non tech press) ... article is a bit too hopeful IMHO: http://www.independent.co.uk/life-style/gadgets-and-tech/news/an-invention-that-could-change-the-internet-for-ever-1678109.html.